Pharmaceutical Grade Analgesic Powder Xylazine CAS 7361-61-7 for Antinociceptive

Analgesic Powder Xylazine CAS: 7361-61-7 Pharmaceutical Grade for Antinociceptive

Basic View:

Product Name: Xylazine
Synonyms: 2-(2,6-dimethylanilino)-5,6-dihydro-4h-1,3-thiazine;2-(2,6-dimethylphenylamino)-4h-5,6-dihydro-1,3-thiazine;5,6-dihydro-2-(2,6-xylidino)-4h-1,3-thiazine;5,6-dihydro-2-(2,6-xylidino)-4h-3-thiazine;bay1470;n-(2,6-dimethylphenyl)-5,6-dihydro-4h-3-thiazine-2-amine;n-(5,6-dihydro-4h-1,3-thiazinyl)-6-xylidine;wh7286
CAS: 7361-61-7
MF: C12H16N2S
MW: 220.33
EINECS: 230-902-1
Chemical Properties White to Off-White Solid
purity: 98%
packing:1kg/foil bag

Description:

Xylazine HCl Injection (xylazine), a non-narcotic compound, is a sedative and analgesic as well as muscle relaxant. Its sedative and analgesic activity is related to central nervous system depression. Its muscle relaxant effect is based on inhibition of the intraneural transmission of impulses in the central nervous system. The principal pharmacological activities develop within 10 to 15 minutes after intramuscular injection in horses and Cervidae, and within 3 to 5 minutes following intravenous administration in horses.

A sleeplike state, the depth of which is dose-dependent, is usually maintained for 1 to 2 hours, while analgesia lasts from 15 to 30 minutes. The centrally-acting muscle relaxant effect causes relaxation of the skeletal musculature, complementing sedation and analgesia.

In horses and Cervidae under the influence of Xylazine HCl Injection (xylazine), the respiratory rate is reduced as in natural sleep. Following treatment with Xylazine HCl Injection (xylazine), the heart rate is decreased and a transient change in the conductivity of the cardiac muscle may occur, as evidenced by a partial atrioventricular block. This resembles the atrioventricular block often observed in normal horses.1,2,3,4 Partial A-V block may occasionally occur following intramuscular injection of Xylazine HCl Injection (xylazine). When given intravenously in horses, the incidence of partial A-V block is higher. Intravenous administration causes a transient rise in blood pressure in horses, followed by a slight decrease.

Xylazine HCl Injection (xylazine) has no effect on blood clotting time or other hematologic parameters.
 

Xylazine Medical Usage:
Xylazine is often used as a sedative, muscle relaxant, and analgesic. It is frequently used in the treatment of tetanus. Xylazine is very similar to drugs such as phenothiazine, tricyclic antidepressants, and clonidine. Yohimbine has been used to decrease glucose levels to a healthy level. In clinical settings, Yohimbine can reverse the adverse effects of xylazine if administered intravenously at a dosage of 0.5 mL / 20 pounds shortly after xylazine administration.

Xylazine Chemistry:
Xylazine hydrochloride, a non-narcotic compound, is a sedative and analgesic as well as a muscle relaxant. Its sedative and analgesic activity is related to central nervous system depression. Following intramuscular administration, the clinical effects of xylazine hydrochloride are apparent within 10-15 minutes. Clinical effects are observed within 3-5 minutes of intravenous administration. A sleeplike state, the depth of which is dose-dependent, is usually maintained for 1 to 2 hours, while analgesia lasts from 15 to 30 minutes.
Xylazine hydrochloride is 2- (2,6-dimethylphenylamino) -4H-5,6-dihydro-1,3-thiazine
hydrochloride.

Xylazine is an analogue of clonidine and an agonist at the α2 class of adrenergic receptor. It is used for sedation, anesthesia, muscle relaxation, and analgesia in animals such as horses, cattle and other non-human mammals.
Usage
Xylazine is recognized as a short-acting tranquilizer or sedative that provides significant pain relief. Acting as a muscle relaxant through its effects on the central nervous system, it is commonly used for short-term sedation, and treatment and management of colic.

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