Product Details:
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| Appearance: | White To Off-white Powder | Storage Temp: | -20°C Freezer |
|---|---|---|---|
| MF: | C21H24N4O2S | Package: | Disguised Package |
| Density: | 1.313 | Molecular Weight: | 396.506 |
| Payment: | T/T, Western Union, Money Gram, Bitcoin | Shipping Method: | EMS, DHL, FedEx, TNT, Hkpost, Hkdhl, Hkems |
| High Light: | pharma raw material.raw pharmaceutical materials,pharmaceutical grade raw materials |
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Supply 99% Purity Pharmaceutical Grade Mirabegron Powder CAS: 223673-61-8 For Overactive Bladder
| English Name | Mirabegron |
| English synonyms | 4-Thiazoleacetamide, 2-amino-N- (4- (2- (((2R) -2-hydroxy-2-phenylethyl) amino) ethyl) phenyl (N-); Mirabegron; 4- (2- (2-HYDROXY-2-PHENYLETHYLAMINO) ethyl) phenyl) -2- (2-aminothiazol-4-yl) acetamide; 2-AMino-N-[4-[2-[[(2R) -2-hydroxy-2-phenyl-ethyl]aMino]-ethyl]phenyl]-4-thiazoleacetaMide; 2- (2-aMino-1,3-thiazol-4-yl) -N- (4-{2-[(2-hydroxy-2-phenylethyl) aMino]ethyl}phenyl) acetaMide; (2R) -2- (2-AMinothiazol-4-yl) -4'-[2-[(2-hydroxy-2-phenylethyl) aMino]ethyl]acetic Acid Anilide; YM 178; Mirabegron (YM 178) |
| CAS | 223673-61-8 |
| Molecular formula | C21H24N4O2S Molecular weight: 396.506 |
| Molecular weight | 396.506 |
| EINECS number | null |
| Related categories | Amines; Aromatics; Heterocycles; Intermediates Chemicals Pharmaceuticals; Sulfur & Fine; Selenium & Compounds; heterocyclic compounds; pharmaceutical raw materials and intermediates; neural signals; pharmaceutical intermediates; small molecule inhibitors |
Description:
Mira peron is a B3 adrenergic receptor agonist, has become a kind of treatment of overactive bladder (overactive bladder OAB) new drug. In order to evaluate Mira peron compared with the efficacy and tolerability of placebo. This study was a multicenter, randomized, double-blind, parallel study (placebo group and Todd Luoding release agent group) phase III clinical trials, conducted in 27 countries in Europe and Australia, with 18 years of age or older, OAB symptoms more than 3 months.
Use in special populations
(1) the pregnancy only if the benefit to the mother outweighs the potential risks to the fetus is only used when.
(2) nursing mothers: Myrbetriq is expected to be excreted in human milk and nursing mothers is not recommended.
(3) children: has not been established in children with Myrbetriq safety and effectiveness.
(4) elderly: proposal on recommends no dose adjustment in elderly patients.
COA:
| Item | Specification | Result |
| Appearance | White crystalline powder | Complies |
| Related substance (HPLC) |
Total impurity ≤0.5% Max single impurity ≤0.1% |
0.2% 0.06% |
| Odor | Characteristic | Complies |
| Assay | 99% | 99.8% |
| Sieve analysis | 100% pass 80 mesh | Complies |
|
Loss on Drying Residue on Ignition |
≤1.0% ≤1.0% |
0.12% 0.09% |
| Heavy Metal | <10ppm | Complies |
| As | <0.1ppm | 0.05ppm |
| Pb | <0.1ppm | 0.05ppm |
| Cd | <0.1ppm | 0.05ppm |
| Residual Solvents | <100ppm | Complies |
| Residual Pesticide | Negative | Complies |
| Microbiology | ||
| Total Plate Count | <1000cfu/g | Complies |
| Yeast & Mold | <100cfu/g | Complies |
| E.Coli | Negative | Complies |
| Salmonella | Negative | Complies |
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