Product Details:
Payment & Shipping Terms:
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| Express Way: | EMS, FedEx, TNT, DHL, Hkems | Alias: | AICAR; AICA-RIBOSIDE; AMPK; Z-RIBOSIDE |
|---|---|---|---|
| Assay: | 98% | Appearance: | White Or Off-white Powder |
| Packing: | Discreet Ways Of Packing For Customs Pass Guaranteed | Specification: | GMP, USP, ISO9001 |
| High Light: | HGH raw powder,raw sarm powder |
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CAS2627-69-2 Aicar/Acadesine Ampk Activator Sarm Raw Powder Nucleoside Analogue White Powder
Quick Detail:
Alias: AICAR;AICA-RIBOSIDE;AMPK;Z-RIBOSIDE
CAS: 2627-69-2
EINECS: 220-097-5
Assay: 98%
Molecular Formula: C9H14N4O5
Molecular Weight: 258.23
Molecular Structure:
Melting Point: 214-215 °C
Storage Instructions:Store at -20°C (desiccating conditions).
Solubility Overview:Soluble in water to 50 mM and in DMSO to 100 mM (with heating)
Properties: white or off-white powder.
Usage: pharmaceutical intermediates.For the treatment of cardiovascular diseases.
Description:
AICAR is a cell permeable activator of AMP-activated protein kinase (AMPK), a metabolic master regulator that is activated in times of reduced energy availability (high cellular AMP:ATP ratios) and serves to inhibit anabolic processes. In vivo, pharmacologic activation of AMPK with AICAR mimics exercise and triggers insulin-independent glucose uptake by skeletal muscle.
AMP-activated protein kinase (AMPK) functions as a metabolic sensor that regulates lipid and glucose metabolism to maintain cellular energy homeostasis and to protect against metabolic stress.AICAR is a selective activator of AMPK in both hepatocytes and adipocytes. At 0.5 mM it inhibits the synthesis of fatty acids and sterols and inactivates HMG-CoA reductase in rat hepatocytes.AICAR (0.5 mM) inhibits insulin-stimulated glucose uptake to 62% of controls and reduces GLUT4 translocation 2.5-fold in 3T3-L1 adipocytes. It also blocks the expression of pro-inflammatory cytokines (TNF-α/IL-1β and IL-6), iNOS, COX-2, and MnSOD genes in glial cells and macrophages by inhibiting NFKB and C/EBP pathways.
Specification:
| Item | Specification | Result |
| Appearance | White powder | Complies |
| Related substance (HPLC) | Total impurity ≤0.5% Max single impurity ≤0.1% |
0.2% 0.06% |
| Odor | Characteristic | Complies |
| Assay | 99% | 99.8% |
| Sieve analysis | 100% pass 80 mesh | Complies |
| Loss on Drying Residue on Ignition |
≤1.0% ≤1.0% |
0.12% 0.09% |
| Heavy Metal | <10ppm | Complies |
| As | <0.1ppm | 0.05ppm |
| Pb | <0.1ppm | 0.05ppm |
| Cd | <0.1ppm | 0.05ppm |
| Residual Solvents | <100ppm | Complies |
| Residual Pesticide | Negative | Complies |
| Microbiology | ||
| Total Plate Count | <1000cfu/g | Complies |
| Yeast & Mold | <100cfu/g | Complies |
| E.Coli | Negative | Complies |
| Salmonella | Negative | Complies |
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FAQ
1.How about parcel delivery success rate ?
Our goods packing will not contain any hormone information and can be sent out from different areas of china. At present,the goods customs clearance rate we send to United states and Europe is 99%. As for Canada, Brazil of quite high buckle close rate area, we also have a new way to get through the customs. We also have completely re-send policy to some areas.
2.What is The Minimum And Maximum Amount Of Steroid Powder I Can Order At One Time?
Normally, our min.order quantity is 10g,please feel free to contact us about the specific order.
We suggest the net weight of each package should be less than 3.5kg. But if your order quantity is more than 3.5 kg, we will split the goods into several packages and then send you separately.
3.Do You Ship Over The Weekend?
We use EMS,TNT,FEDEX,DHL four kinds of couriers. EMS don't collected parcels over the weekend. The packages can be shipped out normally before 12:00 a.m in Beijing time if you choose to ship by TNT or FedEx.
