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Memory Improving Raw Sarm Powder , DM 235 Sunifiram Powder CAS 314728-85-3

Good quality Protein Peptide Hormones for sales
Good quality Protein Peptide Hormones for sales
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Memory Improving Raw Sarm Powder , DM 235 Sunifiram Powder CAS 314728-85-3

China Memory Improving Raw Sarm Powder , DM 235 Sunifiram Powder CAS 314728-85-3 supplier
Memory Improving Raw Sarm Powder , DM 235 Sunifiram Powder CAS 314728-85-3 supplier Memory Improving Raw Sarm Powder , DM 235 Sunifiram Powder CAS 314728-85-3 supplier

Large Image :  Memory Improving Raw Sarm Powder , DM 235 Sunifiram Powder CAS 314728-85-3

Product Details:

Place of Origin: Hunan,China
Brand Name: Muscle Man
Certification: GMP, HSE, ISO 9001, USP, BP
Model Number: CAS: 314728-85-3

Payment & Shipping Terms:

Minimum Order Quantity: 10g
Price: Negotiable
Packaging Details: Discreet Ways Of Packing For Customs Pass Guaranteed
Delivery Time: Within 12 Hours Upon Receipt Of Payment
Payment Terms: Western Union, Money Gram, Bitcoin, Paypal, T/T
Supply Ability: 500-1000kg Per Month
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Detailed Product Description
Purity: 99% Payment Terms: Western Union, Money Gram , T/T, Bitcoin
Origin: China MF: C14H18N2O2
MW: 246.31176 Shelf Life: 2 Years
Appearance: White Powder Boiling Point: ° C At 760 MmHg

Raw Sarms Powder Sunifiram DM-235 CAS 314728-85-3 For Improving Memory Cognition Disorder

 

Sunifiram Quick Detail:

Product Name:Sunifiram;DM-235

English name: 1-(4-Benzoylpiperazin-1-yl)propan-1-one

Synonyms: Sunifiram;DM-235;1-Benzoyl-4-(1-oxopropyl)piperazine
CAS : 314728-85-3
Purity: 99%
Molecular Formula: C14H18N2O2
Molecular Weight: 246.30492
Boiling Point: ° C at 760 mmHg
Appearance: White powder
Shelf life: 2 years
Usage: For the treatment of Alzheimers Dementia, Cognition Disorder, Neurologic Drugs, Senile Dementia, Acetylcholine Release Enhancers.

 

Sunifiram Description:

Sunifiram (DM-235) is a synthetic derivative of piracetam , although due to breaking the pyrrolidone backbone it is no longer in the racetam class of drugs (yet by being derived from them, it is still commonly associated with this class).

Sunifiram has mechanisms similar to nefiracetam in the hippocampus, and similar to that drug sunifiram shows anti-amnesiac properties and is potentially a cognitive enhancer. Its anti-amnesiac activity is several orders of magnitude greater than piracetam on a per weight basis, and preliminary evidence suggest it has a similarly low toxicity profile.

This compound is known as an AMPAkine due to exerting most of its actions via the AMPA receptor (one of the three main subsets of glutamate receptors, alongside NDMA and kainate). This enhancement of AMPA function seems to also rely on enhancing signalling via the glycine binding site of NMDA receptors, although one minimal signalling goes through the NMDA receptor then the benefits on AMPA receptors seem dose-dependent.

 

Sunifiram Applications:

This compound is known as an AMPAkine due to exerting most of its actions via the AMPA receptor (one of the three main subsets of glutamate receptors, alongside NDMA and kainate). This enhancement of AMPA function seems to also rely on enhancing signalling via the Glycine binding site of NMDA receptors, although one minimal signalling goes through the NMDA receptor then the benefits on AMPA receptors seem dose-dependent.

Sunifiram (DM-235) is a piperazine derived ampakine drug which acts as a positive allosteric modulator of AMPA receptors, and has nootropic effects in animal studies with significantly higher potency than piracetam. A number of related compounds are known, the best known being unifiram (DM-232).

This enhancement by sunifiram is associated with an increase inphosphorylation of AMPAR through activation of protein kinase II(CaMKII) and an increase in phosphorylation of NMDAR through activation of protein kinase C α (PKCα). More specifically, sunifiram stimulates the glycine-binding site of NMDAR with concomitant PKCαactivation through Src kinase. Enhancement of PKCα activity triggers to potentiate hippocampal LTP through CaMKII activation.Sunifiram improves cognitive deficits via CaM kinase II andprotein kinase C activation.

 

Memory Improving Raw Sarm Powder , DM 235 Sunifiram Powder CAS 314728-85-3

 

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