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|Suitable For:||Adult||Package:||Discreet Ways Of Packing For Customs Pass Guaranteed|
|Function:||Hormones And Regulation||Usage:||Pharmaceutical Material|
99% Purity Peptides 2mg/10mg Gonadorelin Gonadorelin Acetate 71447-49-9 For Muscle Mass
What is Gonadorelin:
GnRH production/release is one of the few confirmed examples of behavior influencing hormones, rather than the other way around. Cichlid fish that become socially dominant in turn experience an upregulation of GnRH secretion whereas cichlid fish that are socially subordinate have a down regulation of GnRH secretion.Besides secretion, the social environment as well as their behavior affects the size of GnRH neurons. Specifically, males that are more territorial have larger GnRH neurons than males that are less territorial. Differences are also seen in females, with breeding females having smaller GnRH neurons than control females.These examples suggest that GnRH is a socially regulated hormone.
Factrel (gonadorelin) is C 55 H 75 N 17 O 13 HCl, as the mono- or dihydrochloride, or their mixture. The gonadorelin base has a molecular weight of 1182.33. It is a white powder, soluble in alcohol and water, hygroscopic and moisture-sensitive, and stable at room temperature. The synthetic decapeptide, Factrel (gonadorelin) , has a chemical composition and structure identical to the natural hormone, identified from porcine or ovine hypothalami.
Benefit of Gonadorelin:
GnRH activity is very low during childhood, and is activated at puberty or adolescence. During the reproductive years, pulse activity is critical for successful reproductive function as controlled by feedback loops. However, once a pregnancy is established, GnRH activity is not required. Pulsatile activity can be disrupted by hypothalamic-pituitary disease, either dysfunction (i.e., hypothalamic suppression) or organic lesions (trauma, tumor). Elevated prolactin levels decrease GnRH activity. In contrast, hyperinsulinemia increases pulse activity leading to disorderly LH and FSH activity, as seen in polycystic ovary syndrome (PCOS). GnRH formation is congenitally absent in Kallmann syndrome.
Gonadorelin is a medicine that is the same as gonadotropin-releasing that is naturally released from the hypothalamus gland. GnRH causes the pituitary gland to release others (luteinizing hormone [LH] and follicle-stimulating [FSH]). LH and FSH control development in children and fertility in adults. Gonadorelin is used to test how well the hypothalamus and the pituitary glands are working. It is also used to cause ovulation (release of an egg from the ovary) in women who do not have regular ovulation and menstrual periods because the hypothalamus gland does not release enough Gnrh.
How to use Gonadorelin:
Goserelin may cause an increase in certain hormones in the first few weeks after insertion of the implant. Your doctor will monitor you carefully for any new or worsening symptoms during this time.Goserelin comes as an implant to be inserted with a syringe subcutaneously (under the skin) in your stomach area by a doctor or nurse in a medical office or clinic. An implant with 3.6 mg of goserelin is usually inserted every 4 weeks. An implant with 10.8 mg of goserelin is usually inserted every 12 weeks. The length of your treatment depends on the condition being treated and your response to the medication. Your doctor will determine how long you should use goserelin implant.
Gonadorelin is responsible for the release of follicle stimulating hormone and leutinizing hormone from the anterior pitutitary. In the pituitary GnRH stimulates synthesis and release of FSH and LH, a process that is controlled by the frequency and amplitude of GnRH pulses, as well as the feedback of androgens and estrogens. The pulsatility of GnRH secretion has been seen in all vertebrates, and it is necessary to ensure a correct reproductive function. Thus a single hormone, GnRH, controls a complex process of follicular growth, ovulation, and corpus luteum maintenance in the female, and spermatogenesis in the male. Its short half life requires infusion pumps for its clinical use.
|Storage:||Cool(2~8 °C) & dry place|
|Apprarance:||White or slightly yellowish powder White powder|
|Function:||Incresing strength, endurance and performance;stimulates the production of testosterone|
|Minimum Order Quantity:||2mg|
|Payment Terms:||Western Union, MoneyGram, T/T, Bank Transfer;Bitcoin|
|Lead Time:||Within 12 hours after receiving the payment|
|Supply Ability:||Mass in stock|
|CJC 1295 DAC||2mg/vial|
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