Payment & Shipping Terms:
|MW:||466.97||Package:||Foil Bag Or Tin|
|Grade:||Medical Grade||Payment:||T/T, Western Union, MoneyGram, Bitcoin, Bank Transfer|
Strong Glucocorticoid Steroids Powder Clobetasol Propionate CAS: 25122-46-7 for Anti-Inflammatory
Product Name:Clobetasol Propionate
Synonyms:17-propionate;clobesol;pregna-1,4-diene-3,20-dione,21-chloro-9-fluoro-11-beta,17-dihydroxy-16-beta-me;Clobestasol Propionate;Clobetasol-17-Propionate;Clobetasole Propionate
Chemical Properties:White Crystalline Powder
Usage:For short-term topical treatment of the inflammatory and pruritic manifestations of moderate to severe corticosteroid-responsive dermatoses of the scalp.
Packing:1kg/ tin or bag
Clobetasol propionate is a corticosteroid of the glucocorticoid class used to treat various skin disorders including eczema and psoriasis. It is also highly effective for contact dermatitis caused by exposure to poison ivy/oak. Clobetasol belongs to US Class I (Europe: class IV) of the corticosteroids, making it one of the most potent available. It comes in shampoo, mousse, ointment and emollient cream presentations. It has very high potency and typically should not be used with occlusive dressings, or for extended continuous use (beyond two weeks). It is also used to treat several autoimmune diseases including alopecia areata, vitiligo, lichen sclerosus, and lichen planus.
Clobetasol propionate for synthetic efficient local external use of glucocorticoid hormone drugs. Has strong anti-inflammatory, anti itch and capillary contraction, the anti-inflammatory effects of about 112.5 times that of hydrocortisone betamethasone sodium phosphate 2.3 times, 18.7 times fluocinolone. At the same time have the function of the inhibition of cell mitosis, can effectively penetrate into the skin cutin layer.
What Is Clobetasol Propionate is Used For?
A) Clobetasol propionate is used to reduce the inflammation, redness,swelling, itching and tenderness associated with skin conditions and is applied locally on the skin.
B) It is a topical corticosteroid, sometimes known as steroids.
C) It is used to treat skin and scalp conditions that have not been effectively treated with other steroids.
D) In general this drug is used to treat eczema, psoriasis, dermatitis and neurodermatitis (skin problems caused by stress or other psychologicalfactors).
Clobetasol Propionate Application:
Clobetasol propionate is part of a group of drugs known as glucocorticoids, which are a type of corticosteroid (or "steroid" for short). Although glucocorticoids have numerous effects in the body, they are used mostly for their anti-inflammatory or immune-suppressing properties. Clobetasol propionate works for most conditions by decreasing inflammation or suppressing an overactive immune system.
Clobetasol propionate is a corticosteroid of synthetic steroid used to treat various skin disorders including inflammation, itching, herpes labialis, eczema, psoriasis and lichen sclerosus.
Clobetasol propionate is also highly effective for contact dermatitis caused by exposure to poison ivy/oak and auto-immune diseases including alopecia areata, vitiligo, lichen planus (auto immune skin nodules), and mycosis fungoides (T-cell skin lymphoma).
Clobetasol propionate is used as first-line treatment for both acute and chronic GVHD of the skin.
Clobetasol Propionate COA:
|Items of analysis||Specification||Results|
|Description||White or almost white crystalline powder||Almost white crystalline powder|
|Solubility||Practically insoluble in water,slightly soluble in benzene and diethyl ether ,sparingly soluble ethanol, soluble in acetone and in dimethyl sulfoxide, in chloroform, in methanol and in dioxane||Complies|
|Identification (IR)||Complies with the Standard||Complies|
|Melting point||about 196ºC||195.0ºC~197.0ºC|
|Loss on drying||max.2.0%||0.20%|
|Residue on ignition||max. 0.1%||0.04%|
|Single impurity||N.m.t 1.0%||0.16%|
|Sum impurity||N.m.t 2.5%||0.46%|
|Organic volatile impurities||meet the ICH requirement||Complies|
|THF||Not more than 720ppm||Complies|
|Methanol||Not more than 3000ppm||Complies|
|DMF||Not more than 880ppm||Complies|
|Pyridine||Not more than 200ppm||Complies|
|Dichloromethane||Not more than 600ppm||Complies|
|Ethanol||Not more than 5000ppm||Complies|
|Acetone||Not more than 5000ppm||Complies|
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