Payment & Shipping Terms:
|Assay:||99% Min||Payment Terms:||Western Union, MoneyGram, T/T,Bitcoin,Paypal.|
99.8% purity Safe Muscle Building Prohormones Raw Hormone Powders Tibolone CAS 5630-53-5
Synonyms: TIBOLONE; LIVIELLA; LIVIAL
Assay: 99% min.
Packing: 1kg/foil bag.
Delivery: Express courier.
Character: White powder.
Usage: pharmaceutical material, Steroid hormone, Anabolin. A synthetic steroid with weak estrogenic, androgenic and progestogenic activity. A pharamceutical used in the treatment of menopausal syndrome.
Tibolone (Livial/Liviella) is used mainly for treatment of endometriosis, as well as hormone replacement therapy in post-menopausal women. Tibolone is a synthetic steroid hormone drug, which is fairly non-selective in its binding profile, acting as an agonist mainly at estrogen receptors, with a preference for ER alpha. Tibolone has similar or greater efficacy compared to older hormone replacement drugs, but shares a similar side effect profile. It has also been investigated as a possible treatment for female sexual dysfunction.
Tibolone possesses a complex pharmacology. Its two major active metabolites, 3α-hydroxytibolone and 3β-hydroxytibolone, act as potent, fully activating agonists of the estrogen receptor , with a high preference for ERα. Tibolone and its metabolite 4-tibolone act as agonists of the progesterone and androgen receptors, while 3α-hydroxytibolone and 3β-hydroxytibolone, conversely, act as antagonists of these receptors. Lastly, tibolone, 3α-hydroxytibolone, and 3β-hydroxytibolone act as antagonists of the glucocorticoid and mineralocorticoid receptors, with preference for the mineralocorticoid receptor.
Tibolone has tissue-selective estrogenic effects, with desirable effects in bone, the brain, and the vagina, and lack of undesirable action in the endometrium and breasts.Its tissue selectivity is the result of metabolism, enzyme modulation (e.g., of estrogen sulfatase and estrogen sulfotransferase), and receptor modulation that vary in different target tissues, and differs mechanistically from that of selective estrogen receptor modulators (SERMs) such as tamoxifen, which produce their tissue-selectivity via means of modulation of the ER. As such, to distinguish it from SERMs, tibolone has been described as a "selective tissue estrogenic activity regulator" (STEAR), and also as a "selective estrogen enzyme modulator"
A: Zhuzhou Interial Biotechnology Co., Ltd is a renowned pharmaceutical manufacturer, specializing in raw steroid powders in Mainland, China. All powders are factory directly supplying.
B: Our products have been exported to Germany, Norway, Poland, Finland, Spain, UK, France, Russia, USA, Brazil, Mexico, Australia, Japan, Korea, Thailand, Indonesia, Uruguay and almost around the world.
C: Our products are of high quality at competitive prices. Free samples are available.
D:Well discreet packing. Fast and secure delivery by DHL, TNT, FedEx, HKEMS, UPS, etc.
E: Flexible and untraceable payment terms.
F Exclusive customer service and 24/7 online timely and helpful after-sale service.
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