Payment & Shipping Terms:
|Packing:||Discreet Package To Pass The Customs.||Purity:||>99%|
|MW:||453.5||Certification:||GMP, HSE, ISO 9001, USP, BP|
SARMS Raw Powder SARMS GW 501516 Fat Loss Powder CAS 317318-70-0 With 99.8% Assay
Assay: 98.0%--102.0%. USP32
What is GW-501516:
GW501516 (GW1516 or GSK-516) is a drug that acts as a PPARd modulator. GW 501516 activates AMP-activated protein kinase and stimulates glucose uptake in skeletal muscle tissue, and GW 501516 has been demonstrated to reverse metabolic abnormalities in obese men with pre-diabetic metabolic syndrome, most likely by stimulating fatty acid oxidation. It has been proposed as a potential treatment for obesity and related conditions, especially when used in conjunction with a synergistic compound AICAR, as the combination has been shown to significantly increase exercise endurance in animal studies. GW-50156 regulates fat burning through a number of widespread mechanisms; it increases glucose uptake in skeletal muscle tissue and increases muscle gene expression, especially genes involved in preferential lipid utilization. This shift changes the body's metabolism to favor burning fat for energy instead of carbohydrates or muscle protein, potentially allowing clinical application for obese patients to lose fat effectively without experiencing muscle catabolism or the effects and satiety issues associated with low blood sugar. GW-501516 also increases muscle mass, which improved glucose tolerance and reduced fat mass accumulation even in mice fed a very high fat diet, suggesting that GW-501516 may have a protective effect against obesity.
GW-501516 Functions and Traits:
GW-501516 binds to the PPAR receptor, specifically a group of nuclear receptors (sensors that detect thyroid
and steroidal hormones in the body) that initiates the PGC-1a enzyme. This action leads to gene expression,
specifically genes that revolve around energy expenditure.
Studies involving GW-501516 have shown to increase the metabolism of fatty acids in rats. It was also shown in the same studies to reduce the odds of obesity despite poor eating habits as well as prevent Type-2 diabetes. GW-501516 was also shown to increase HDL (good cholesterol) and decrease LDL (bad cholesterol) in a study using monkeys. The effects seemed to hold true with or without exercise.
SARMs Supplying List:
|Selective Androgen Receptor Modulators Supplying List|
|Product Name||CAS Number||Product Name||CAS Number|
|Ostarine, MK-2866,||841205-47-8; 1202044-20-9||GW-501516||317318-70-0|