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SARMS Raw White Powder 99% GW-501516 Cardarine Regulates Fat Burning CAS 317318-70-0
Assay: 98.0%--102.0%. USP32
What is GW-501516:
GW501516 (GW1516 or GSK-516) is a drug that acts as a PPARd modulator. GW 501516 activates AMP-activated protein kinase and stimulates glucose uptake in skeletal muscle tissue, and GW 501516 has been demonstrated to reverse metabolic abnormalities in obese men with pre-diabetic metabolic syndrome, most likely by stimulating fatty acid oxidation. It has been proposed as a potential treatment for obesity and related conditions, especially when used in conjunction with a synergistic compound AICAR, as the combination has been shown to significantly increase exercise endurance in animal studies. GW-50156 regulates fat burning through a number of widespread mechanisms; it increases glucose uptake in skeletal muscle tissue and increases muscle gene expression, especially genes involved in preferential lipid utilization. This shift changes the body's metabolism to favor burning fat for energy instead of carbohydrates or muscle protein, potentially allowing clinical application for obese patients to lose fat effectively without experiencing muscle catabolism or the effects and satiety issues associated with low blood sugar. GW-501516 also increases muscle mass, which improved glucose tolerance and reduced fat mass accumulation even in mice fed a very high fat diet, suggesting that GW-501516 may have a protective effect against obesity.
GW-501516 Functions and Traits:
GW-501516 binds to the PPAR receptor, specifically a group of nuclear receptors (sensors that detect thyroid
and steroidal hormones in the body) that initiates the PGC-1a enzyme. This action leads to gene expression,
specifically genes that revolve around energy expenditure.
Studies involving GW-501516 have shown to increase the metabolism of fatty acids in rats. It was also shown in the same studies to reduce the odds of obesity despite poor eating habits as well as prevent Type-2 diabetes. GW-501516 was also shown to increase HDL (good cholesterol) and decrease LDL (bad cholesterol) in a study using monkeys. The effects seemed to hold true with or without exercise.
Effects of GW-501516:
The effects of GW-501516 are fairly significant and may be a welcomed addition to the stack for a performance athlete. Increased endurance may be the PPAR-RA's most incredible attribute. Those who use the medication will find they do not tire out as easily and can train harder and longer. The cardiovascular endurance that comes with GW-501516 is so strong it has been shown to do away with the cardio issues that surround the popular anabolic steroid . Many who use Trenbolone report breathing becomes a bit more difficult and that cardio becomes a more arduous task. GW-501516 seems to negate this negative effect when using Tren.
The effects of GW-501516 also help tremendously with fat loss. If nothing else, you're able to perform your cardio more intensely and longer. Further, it doesn't carry any catabolic effect that is associated with many thermogenics or fat burners, meaning muscle loss due to use is of no concern. More importantly, GW-501516 has been shown to increase nutrient efficiency. Simply put, you make better use of the nutrients you're consuming. Those who use the compound will find increased levels of glucose uptake and fat stores reduced.
Availability of GW-501516:
GW-501516 is available through some research chemical companies although not one of the more common
products carried. You may also find some anabolic steroid suppliers that carry it; however, the latter will not be
a legal purchase. Research chemical companies exist due to a gray area of the law, and while purchasing is
legal, it is only legal for research purposes.
Based on its positive attributes, GW-501516 may be one of the single best products an athlete could buy. However, although not an anabolic steroid, numerous sporting bodies have already banned it and it will show up in sports doping tests. But when it comes to the benefits, endurance and enhancing nutrient efficiency are two benefits that are hard to beat. It's hard to beat this into the head of many athletes, recovery, endurance and food itself are the three most important factors associated with making gains or improving performance, and GW-501516 does just that.
Although the benefits of GW-501516 are undeniable, we are still left with the glaring possibility of use-induced cancer. Regardless of how much muscle you carry or how low your body fat is, cancer is going to ruin the physique you've built, not to mention your life. The odds of cancer, from looking at some of the studies that were done they do appear to be somewhat flawed, while others scream warning. It is truly hard to say what would happen if you were to try this drug, but there does appear to be a legitimate risk, and enough of one to cause a very large pharmaceutical giant to completely give up on what could have been a highly profitable drug had the cancer scare not existed.
|ANALYTICAL ITEMS||SPECIFICATION||ANALYTICAL RESULTS|
|Appearance||White Powder||White powder|
|Melting Point||134°C~ 136°C||134°C|
|Related substances||A single impurity≤0.5%||0.15%|
|Loss on drying||≤0.5%||0.15%|
|Conclusion||Confirms to Enterprise Standard|
SARMs Supplying List:
|Selective Androgen Receptor Modulators Supplying List|
|Product Name||CAS Number||Product Name||CAS Number|
|Ostarine, MK-2866,||841205-47-8; 1202044-20-9||GW-501516||317318-70-0|